Stuart Hameroff’s research pursued microtubule information processing and anesthetic action. In the mid-1990s he teamed with eminent British physicist and Nobel Laureate Sir Roger Penrose to develop a controversial quantum theory of consciousness (‘orchestrated objective reduction’, ‘Orch OR’) based on microtubule quantum computing. Harshly criticized initially, Orch OR is now supported by experimental results including anesthetic action. In 2017, with Sir Roger Penrose, James Tagg, Ivette Fuentes and Erik Viierre, Hameroff co-founded the Penrose Institute, intended to support research based on the various works of Sir Roger (cosmology, quantum mechanics, general relativity, black holes, geometry and consciousness)
Stuart Hameroff MD and Sir Roger Penrose
Hameroff, Stuart, ‘Orch OR’ is the most complete, and most easily falsifiable theory of consciousness, (2020) Cognitive Neuroscience, DOI: 10.1080/17588928.2020.1839037 To link to this article: https://doi.org/10.1080/17588928.2020.1839037 - Published online: 24 Nov 2020.
Kalra, Aarat P, Stuart Hameroff, Jack Tuszynski, and Aristide Dogariu. 2020. “Anesthetic Gas Effects on Quantum Vibrations in Microtubules – Testing the Orch OR Theory of Consciousness.” OSF. August 21. 2020 osf.io/zqnjd
Craddock TJA, Kurian P, Preto J, Sahu K, Hameroff SR, Klobukowski M, Tuszynski JA. Scientific Report, 2017, August. Anesthetic Alterations of Collective Terahertz Oscillations in Tubulin Correlate with Clinical Potency: Implications for Anesthetic Action and Post-Operative Cognitive Dysfunction.
Stuart R. Hameroff, Roger Penrose, Chapter 14 "Consciousness in the Universe: An Updated Review of the "Orch OR" Theory, in Biophysics of Consciousness: A Foundational Approach, eds. Roman R. Poznanski, Jack A. Tuszynski, Todd E. Feinberg, World Scientific, 2016.
Craddock, Travis J.A., Stuart R. Hameroff, Ahmed T. Ayoub, Mariusz Klobukowski, & Jack A. Tuszynski. (2015). “Anesthetics act in quantum channels in brain microtubules to prevent consciousness.” Current Topics in Medicinal Chemistry, Vol 15:6, 523-533.
Japan Wired Magazine - 2014 Death in A Quantum Space.pdf - interview with Stuart Hameroff
DEATH IN A QUANTUM SPACE. ハメロフ博士の. 世界一ぶっとんだ死の話. 意識と「量子もつれ」と不滅の魂. 人がその生をまっとうし、肉体が生命活動を終え ...
Craddock, Travis John Adrian, Douglas Friesen, Jonathan Mane, Stuart Hameroff, & Jack A. Tuszynski. (2014). “The Feasibility of Coherent Energy Transfer in Microtubules.” Journal of the Royal Society Interface. 11(100).
Hameroff S., (2014). Comment. L Turin et al, Proc. Nat. Acad. Sci., “Electron spin change during general anesthesia.” Aug. 11.
Response Hameroff to L. Turin et al., 12 August, (2014). pdf. Ref: Hadlington, Simon. “Knock-out theory puts new spin on general anaesthesia.” ChemistryWorld Review, 12 August, (2014) Ref: citation in Luca Turin et al. (2014). “Electron spin changes during general anesthesia in Drosophilia. Proc. Nat. Acad. Sci.,10.1073/ pnas. 1404387111. 26 April, (2014). Ref: Hameroff, SR. (2006). “The entwined mysteries of anesthesia and consciousness: Is there a common underlying mechanism?” Anesthesiology 105(2):400–412.
Hameroff, S., & Roger Penrose (2014). Consciousness in the universe: A review of the ‘Orch OR’ theory.” (2014). Physics of Life Reviews, March 11(1):39-78. pdf. – PhysOrg. Discovery of quantum vibrations in ‘microtubules’ corroborates theory of consciousness. 16 January.
Hameroff, S. (2013). Comment on: A Tale of Two Fields: “Dissipation of ‘dark energy’ by cortex in knowledge retrieval” by Capolupo, Freeman and Vitiello. Phys Life Rev. March; 10(1):95-6; discussion 112-6.
Hameroff S, Trakas M, Duffield C, Annabi E, Gerace MB, Boyle P, Lucas A, Amos Q, Buadu A, Badal JJ, Transcranial ultrasound (TUS) effects on mental states: a pilot study, Brain Stimul, 2013; May;6(3):409-15.
Craddock T, St George M, Freedman H, Barakat K, Damaraju S, Hameroff S, Tuszynski J., Computational Predictions of Volatile Anesthetic Interactions with the Microtubule Cytoskeleton: Implications for Side Effects of General Anesthesia, PLOS One, 2012; June 25
Craddock TJ, St. George Marc, Freedman Holly, Barakat Khaled, Damaraju Sambasivarao, Hameroff Stuart, Tuszynski Jack A., Computational Predictions of Volatile Anesthetic Interactions with the Microtubule Cytoskeleton: Implications for Side Effects of General Anesthesia,PLoS One, 2012; June 25.
Hameroff S., Quantum brain biology complements neuronal assembly approaches to consciousness: Comment on "Consciousness, biology and quantum hypotheses" by Baars and Edelman. Phys Life Rev. 2012 Sep;9(3):303-5; discussion 306-7.